Results 101 to 110 of about 6,115 (211)
Urine Pigments after Ingestion of Phenacetin
Pigments occurring in urine of patients who had ingested analgesics containing phenacetin were studied by several methods including gel filtration and paper chromatography. Pigmentation usually developed several hours after urine was voided.
N. T. Shahidi, M. H. Gault
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FORENSIC ANALYSIS OF COCAINE SAMPLES PRODUCED IN COLOMBIA: I. CHROMATOGRAPHIC PROFILING
In this study sixty-five (65) seized samples of cocaine hydrochloride are chromatographically outlined to determine its purity and making qualitative analysis to detect adulterants and occluded residual reliable extenders in tropacocaine, norcocaine, cis-
William F. GARZÓN M. +2 more
doaj
The formation of solid dispersions is one of the methods of drug hydrophilization. The method of low-temperature differential scanning calorimetry showed the possibility to obtain phenacetin solid dispersions with polyethylene glycol and Pluronic F127 ...
Gerasimov A. +2 more
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A case of renal pelvic tumor due to phenacetin abuse [PDF]
65歳女.慢性頭痛のためセデス末(フェナセチン含有量400mg/包)を内服していたが, その後, 市販薬のセデスA錠(フェナセチン含有せず)に内服変更していた.又, 近医の処方によりサリイタミン(フェナセチン含有量250mg/包)2包/日を内服していた.通算のフェナセチン総摂取量は約8kgであった.無症候性肉眼的血尿で受診した.DIPにより左腎盂腫瘍と診断した.左腎盂尿管全摘出術を施行した.術後経過は良好で退院し, 経過観察中である.組織学的所見は移行上皮癌grade 2で ...
小島, 圭太郎 +5 more
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Stearic acid or hard paraffin added to crystals of paracetamol and phenacetin reduced capping of tablets prepared by direct compression but did not produce acceptable tablets because the inter-particular bonds were very weak.
E Shotton, B A Obiorah
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Adulterants in crack cocaine in Brazil
Introduction Brazil is the world’s biggest consumer of crack cocaine, and dependence is a major public health issue. This is the first study to investigate the prevalence of potentially harmful adulterants present in hair samples from Brazilian patients
Marcelo Ribeiro +10 more
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Mechanistic insights into the bioactivation of phenacetin to reactive metabolites: A DFT study
The knowledge of biochemical mechanism of cancer induction and carcinogenicity by drugs is an essential requisite for drug metabolism and toxicity studies. Metabolic bioactivation of phenacetin leads to the generation of several reactive metabolites (RMs)
Bharatam, Prasad V. +2 more
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To assess potential ethnic and gender-related differences in the expression of cytochrome CYP1A2-mediated activity, the pharmacokinetics of phenacetin (a CYP1A2 substrate) and its metabolite paracetamol were compared in 20 Caucasian and 20 Chinese ...
S. Xiaodong +5 more
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The effect of active and passive cigarette smoking on CYP1A2-mediated phenacetin disposition was evaluated in a controlled study of 36 healthy Chinese subjects.
Shu CC +7 more
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