Results 291 to 300 of about 354,000 (376)

Multigram‐scale organic synthesis by Resonant Acoustic Mixing. Application to the Sustainable Preparation of Active Pharmaceutical Ingredients.

ChemSusChem, Accepted Article.
Three different reaction types were extensively studied at multi‐gram scale by Resonant Acoustic Mixing (RAM): i) the Knoevenagel condensation to vanillin barbiturate, ii) the Biginelli multicomponent reaction (MCR) to dihydropyrimidinones, which includes the anticancer drug (±)‐Monastrol, and iii) the Biltz synthesis to the antiepileptic drug ...
Christos Chatzigiannis, Stefania Scalzullo, Evelina Colacino, Maria Elena Rivas-Velazco   +3 more
wiley   +1 more source

Low rate of rescue epidural analgesia after open colorectal surgery with intrathecal morphine: a retrospective cohort study. [PDF]

Int J Colorectal Dis
de Brun S, Chabok A, Engdahl M, Östberg E.   +3 more
europepmc   +1 more source

Containerless emulsification of acoustically levitated composite drop

Droplet, EarlyView.
Emulsions are inherently thermodynamically unstable dispersions that are widely involved in food processing, cosmetic preparation, and drug delivery. The existing ultrasonic emulsification techniques mainly rely on the direct contact between the sonicator probe and liquids, which caused localized high temperature and pressure within the liquid and ...
Mengchen Cui, Hongyue Chen, Xiuxing Tang, Yutong Guo, Xianyu Nong, Changlin Ding, Zhijun Wang, Xin Gao, Duyang Zang   +8 more
wiley   +1 more source

Effect of a Single Preventive Intravenous Dose of Ketorolac and Paracetamol on Reducing Postoperative Pain in Septorhinoplasty Patients: Double-Blind Randomized Clinical Trial. [PDF]

Iran J Med Sci
Dehghanpisheh L, Jamshidi F, Khademi S, Farokhiani S, Cheraghi MR, Emadi M, Kaboodkhani R, Akbari A, Asmarian N, Banifatemi M.   +9 more
europepmc   +1 more source

Lipid and Corticosteroid Biomarkers Under the Influence of Bisphosphonates

Drug Testing and Analysis, EarlyView.
The detection of bisphosphonates is important due to the potential integrity and welfare issues associated with use of these substances. Targeted detection of a nitrogenous and non‐nitrogenous bisphosphonate was detected for 8 h and 28 days post‐administration, respectively.
Kathy Tou, Adam Cawley, Glenys Noble, Jaymie Loy, David Bishop, John Keledjian, Kireesan Sornalingam, Stacey Richards, Shanlin Fu   +8 more
wiley   +1 more source

A Randomized Controlled Trial Assessing the Effect of Preoperative Ibuprofen Administration on Postoperative Pain Reduction Following Miniscrew Insertion. [PDF]

BMC Oral Health
Zhang HY, Rui CC, Su LW, Xiao YJ, Nie MD, Sun H, Wu Y.   +6 more
europepmc   +1 more source

Waxy‐ or Putty‐Like Materials as a Novel Drug Preparation for Synthetic Cannabinoid Receptor Agonists: Detection in Prisons and In Vitro Cannabinoid Receptor Activity

Drug Testing and Analysis, EarlyView.
Waxy‐ or putty‐like materials has emerged as a novel drug preparation for synthetic cannabinoids and other drugs in UK prisons. An in vitro CB1 bioassay was used to evaluate the CB1 activating potential of MDMB‐INACA and extracts from eight seized samples. MDMB‐INACA had moderate efficacy but low potency at CB1.
Axelle Timmerman, Marie H. Deventer, Rachael Andrews, Robert Reid, Victoria Marland, Darren Edwards, Christopher R. Pudney, Niamh Nic Daéid, Christophe P. Stove, Caitlyn Norman   +9 more
wiley   +1 more source

Liposomal bupivacaine as one component of the postoperative management of limb amputations in cats: a retrospective study. [PDF]

J Feline Med Surg
Schrock K, Gallaher HM, Wilson DV, Beaty B.   +3 more
europepmc   +1 more source

Comprehensive Qualitative Drug Screening in Emergency Toxicology Using an Automated LC–MSn System:Simultaneous Quantification of Relevant Drugs and Metabolites in Blood Plasma

Drug Testing and Analysis, EarlyView.
Simultaneous qualitative and quantitative analysis of 62 drugs and seven active metabolites in human blood plasma by automated liquid chromatography linear ion trap mass spectrometry. ABSTRACT Rapid and comprehensive qualitative and quantitative analytical procedures are crucial in 24/7 emergency toxicology (ET) to support diagnosis and treatment of ...
Selina Hemmer, Maximilian Ninnig, Lea Wagmann, Sascha K. Manier, Markus R. Meyer   +4 more
wiley   +1 more source

Mirtazapine Is Associated With Shorter Hospital Stay in Pediatric Avoidant Restrictive Food Intake Disorder—A Retrospective Chart Review

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Avoidant restrictive food intake disorder (ARFID) is a relatively new diagnostic entity, and no medication has been approved. Recent data suggest that mirtazapine, a tetracyclic antidepressant, could improve outcomes in ARFID. We conducted a retrospective chart review to examine the effects of mirtazapine on ARFID treatment in youth.
Aman Chishti, Rachael E. Groh, Tamara R. Maginot, Lisa Adler, Megan E. Shott, Walter H. Kaye, Guido K. W. Frank   +6 more
wiley   +1 more source