Results 31 to 40 of about 129,583 (223)
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Small, low power analog-to-digital converter [PDF]
, 1968 A small, low-power, high-speed, 8-bit analog-to-digital converter using silicon chip integrated circuits is suitable for use in airborne test data systems.
Dunn, R. D., Fullerton, D. H.
core +1 more source
, 2008 Analog-to-digital conversion and its reverse, digital-to-analog conversion, are ubiquitous in all modern electronics, from instrumentation and telecommunication equipment to computers and entertainment.
Belleman, J
core +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Analog-to-digital conversion system Patent [PDF]
, 1965 Conversion system for increasing resolution of analog to digital ...
Mazer, L.
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
The new CAS-DIS digital ionosonde
Annals of Geophysics, 2013 A high quality digital ionosonde called the Chinese Academy of Sciences digital ionosonde (CAS-DIS) has been developed for investigations of the ionosphere.
Wang Shun +3 more
doaj +1 more source
Fourier waveform analyzer [PDF]
, 1975 Real-time Fourier analysis is provided by "bucket brigade' charge-transfer shift register. Device is small, inexpensive integrated circuit which does analog-to-digital-to-analog conversion, data processing, and time ...
Sutton, J. F.
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source