Results 91 to 100 of about 5,558,287 (332)
Analog System High-Level Synthesis for Energy-Efficient Reconfigurable Computing
, 2023 The design of analog computing systems requires significant human resources and domain expertise due to the lack of automation tools to enable these highly energy-efficient, high-performance computing nodes.
Hang Yang +4 more
core +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Communications Physics, 2021 Analog Ising machines are promising fast computing schemes for some difficult optimization problems, yet their analog nature is known to cause errors and inhibit computational performance.
Fabian Böhm +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Optical differentiation based on the Brewster effect [PDF]
Компьютерная оптика, 2018 In this work, technologies of analog optical computing for image edge detection using flat interfaces between dielectrics are studied both theoretically and experimentally.
Dmitry Nesterenko +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Analog Computing With Hybrid Couplers and Phase Shifters [PDF]
IEEE transactions on microwave theory and techniquesAnalog computing with microwave signals can enable exceptionally fast computations, potentially surpassing the limits of conventional digital computing.
Matteo Nerini +2 more
semanticscholar +1 more source
From analogy-making to modelling : the history of analog computing as a modelling technology [PDF]
Today, modern computers are based on digital technology. However, during the decades after 1940, digital computers were complemented by the separate technology of analog computing.
Care, Charles
core
Analog Computing with Metatronic Circuits
, 2020 Analog photonic solutions offer unique opportunities to address complex computational tasks with unprecedented performance in terms of energy dissipation and speeds, overcoming current limitations of modern computing architectures based on electron flows
Mario Miscuglio (3330321) +7 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source