Results 111 to 120 of about 5,558,287 (332)
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Utilizing rate-independent hysteresis for analog computing
Neuromorphic Computing and EngineeringPhysical systems exhibiting hysteresis are increasingly being used in neuromorphic and in-memory computing research. Generally, the resistance switching of devices with rate-independent hysteresis are being investigated for their use as trainable weights
Lina Jaurigue, Kathy Lüdge
doaj +1 more source
Reconfigurable Analog Computers
2025 Kleinheubach ConferenceThe Achilles heel of classic analog computers was the complex, error prone, and time consuming process of programming. This typically involved manually patching hundreds or even thousands of connections between individual computing elements as well as setting many precision 10-turn potentiometers manually, often taking hours, or even days. Albeit being
openaire +3 more sources
Distributed In-Memory Computing on Binary RRAM Crossbar
, 2017 The recently emerging resistive random-access memory (RRAM) can provide nonvolatile memory storage but also intrinsic computing for matrix-vector multiplication, which is ideal for the low-power and high-throughput data analytics accelerator performed in
Hao Yu +9 more
core +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Analog Computing for Nonlinear Shock Tube PDE Models: Test and Measurement of CMOS Chip
IEEE AccessLong left ignored by the digital computing industry since its heyday in 1940’s, analog computing is today making a comeback as Moore’s Law slows down.
Hasantha Malavipathirana +5 more
doaj +1 more source
PICO-RAM: A PVT-Insensitive Analog Compute-In-Memory SRAM Macro With In Situ Multi-Bit Charge Computing and 6T Thin-Cell-Compatible Layout [PDF]
IEEE Journal of Solid-State CircuitsAnalog compute-in-memory (CIM) in static random access memory (SRAM) is promising for accelerating deep learning inference by circumventing the memory wall and exploiting ultra-efficient analog low-precision arithmetic.
Zhiyu Chen +8 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
On the Non-associativity of Analog Computations
Published at the ECML PKDD Conference 2023, at the 4th Workshop on IoT, Edge, and Mobile for Embedded Machine ...
Lisa Kuhn +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source