Results 91 to 100 of about 298,889 (339)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

0.5V 3rd-order Tunable gm-C Filter [PDF]

, 2013
This paper proposes a 3rd-order gm-C filter that operates with the extremely low voltage supply of 0.5V. The employed transconductor is capable for operating in an extremely low voltage power supply environment.
Arya, R., Psychalinos, C., Souliotis, G., Vlassis, S.   +3 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Design and Development of an Electronic Interface for Acquiring Signals from a Piezoelectric Sensor for Ultrasound Imaging Applications

Technologies
The increasing demand for accurate and accessible medical imaging has driven efforts to develop technologies that overcome limitations associated with conventional imaging techniques, such as MRI and CT scans.
Elizabeth Espitia-Romero, Adriana Guzmán-López, Micael Gerardo Bravo-Sánchez, Juan José Martínez-Nolasco, José Alfredo Padilla Medina, Francisco Villaseñor-Ortega   +5 more
doaj   +1 more source

Digital input is buffered to real-time analog display [PDF]

, 1970
Buffering technique utilizes nine-bit binary counter and holding register of eight flip-flops. These flip-flops form the memory device that allows precise asynchronous conversion of the digital source data.
Bower, K. F.
core   +1 more source

Critical bursts in filtration

, 2017
Particle detachment bursts during the flow of suspensions through porous media are a phenomenon that can severely affect the efficiency of deep bed filters.
Bianchi, Filippo, de Arcangelis, Lucilla, Herrmann, Hans J., Thielmann, Marcel   +3 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

A Hybrid Gain Analog Offline EnKF for Paleoclimate Data Assimilation

Journal of Advances in Modeling Earth Systems
For Paleoclimate data assimilation (PDA), a hybrid gain analog offline ensemble Kalman filter (HGAOEnKF) is proposed. It keeps the benefits of the analog offline ensemble Kalman filter (AOEnKF) that constructs analog ensembles from existing climate ...
Haohao Sun, Lili Lei, Zhengyu Liu, Liang Ning, Zhe‐Min Tan   +4 more
doaj   +1 more source