Results 71 to 80 of about 298,426 (292)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
A microprocessor based anti-aliasing filter for a PCM system [PDF]
Described is the design and evaluation of a microprocessor based digital filter. The filter was made to investigate the feasibility of a digital replacement for the analog pre-sampling filters used in telemetry systems at the NASA Ames-Dryden Flight ...
Morrow, D. C., Sandlin, D. R.
core +1 more source
Novel CCII-based Field Programmable Analog Array and its Application to a Sixth-Order Butterworth LPF [PDF]
, 2013 In this paper, a field programmable analog array (FPAA) is proposed. The proposed FPAA consists of seven configurable analog blocks (CABs) arranged in a hexagonal lattice such that the CABs are directly connected to each other.
Mahmoud, S. A., Soliman, E. A.
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Versatile Tunable Voltage-Mode Biquadratic Filter and Its Application in Quadrature Oscillator
Sensors, 2019 This paper presents a versatile tunable voltage-mode biquadratic filter with five inputs and three outputs. The proposed filter enjoys five single-ended output operational transconductance amplifiers (OTAs) and two grounded capacitors.
San-Fu Wang +3 more
doaj +1 more source
Design Optimization of PMU Anti-Aliasing Filters using Taguchi Method
Algerian Journal of Signals and Systems, 2020 A Phasor Measurement Unit (PMU) is a monitoring device, which serves in checking the power system condition by measuring voltage and current phasors along with frequency at a particular node.
Fatma Zohra DEKHANDJI
doaj +1 more source
Rocket noise filtering system using digital filters [PDF]
A set of digital filters is designed to filter rocket noise to various bandwidths. The filters are designed to have constant group delay and are implemented in software on a general purpose computer. The Parks-McClellan algorithm is used.
Mauritzen, David
core +1 more source