AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Short Transient Parameter-Varying IIR Filter Based on Analog Oscillatory System
This paper presents a concept for digital infinite impulse response (IIR) lowpass filter with reduced transient response. The proposed digital filtering structure is based on an analog oscillatory system. In order to design the considered digital filter,
Piotr Okoniewski, Jacek Piskorowski
doaj +1 more source
A Configurable Interface for Analog Sensor Outputs
Reading out analog sensor outputs can be a challenging task at low frequencies because of the low frequency noise. To obtain a sensor signal clearly, special interface circuits are required. By using such circuits, analog signals are cleaned from offset,
Faik Başkaya, Baran Demirer
doaj +1 more source
Compressed Sensing Based Direct Conversion Receiver With Interference Reducing Sampling
This paper describes a direct conversion receiver applying compressed sensing with the objective to relax the analog filtering requirements seen in the traditional architecture.
Arildsen, Thomas +2 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
CMOS mixed-signal MODEM for data transmission and control of electrical household appliances using the low-voltage power-line [PDF]
This paper presents a CMOS 0.6μm mixed-signal MODEM ASIC for data transmission using the low-voltage power line. This circuit includes all the analog blocks needed for input interfacing and modulation/demodulation (PLL-based frequency synthesis, slave ...
Domínguez Matas, Carlos +4 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
In this paper, the design of a universal second-order filter using configurable analog blocks (CABs) for field programmable analog arrays is presented.
M. T. Abuelma'atti, O. O. Fares
doaj +1 more source
Two techniques for digital filter design [PDF]
Digital controllers, one using a special-purpose computer and the other using a combination of digital and analog techniques, are designed around /1/ computers that simulate the transfer function and interface with the system, and /2/ analog and digital ...
Carroll, C. C. +2 more
core +1 more source
On the development of a MODEM for data transmission and control of electrical household appliances using the low-voltage power-line [PDF]
This paper presents a CMOS 0,6μm mixed-signal MODEM ASIC for data transmission on the low-voltage power line. The circuit includes all the analog circuitry needed for input interfacing and modulation/demodulation (PLL-based frequency synthesis, slave ...
Domínguez Matas, Carlos +4 more
core +1 more source

