Results 41 to 50 of about 71,000 (262)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Analysis and Design of M-Channel Hybrid Filter Bank With Digital Calibration

IEEE Access, 2018
Hybrid filter bank (HFB) is widely used in frequency-interleaved analog-to-digital converters, but traditional HFB structures suffer various degrees of imperfections. This paper presents a new-structure HFB based on power complementary pair. The proposed
Xiangyu Peng, Jingyu Li, Xiaotian Zhou, Qianqiang Lin, Zengping Chen   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Short Transient Parameter-Varying IIR Filter Based on Analog Oscillatory System

Applied Sciences, 2019
This paper presents a concept for digital infinite impulse response (IIR) lowpass filter with reduced transient response. The proposed digital filtering structure is based on an analog oscillatory system. In order to design the considered digital filter,
Piotr Okoniewski, Jacek Piskorowski
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Circuit analysis of RC integration circuits for use in PWM-based DACs

Известия Томского политехнического университета: Промышленная кибернетика
In scientific, educational, and engineering settings, it is often necessary to transmit analog signals to control various actuators. Examples of such devices include motors, valves, dampers, lighting, and audio equipment.
Kirill A. Volobuev, Violetta M. Moskaleva, Igor V. Trubin, Vitaly G. Trubin   +3 more
doaj   +1 more source

Design of a Tunable 4th Order OTA-C Band-Pass Filter for Use in Front-End of ADC [PDF]

Journal of Applied Research in Electrical Engineering
This article presents a tunable fourth-order band-pass filter that is designed using an operational trans-conductance amplifier (OTA), which can be used as an anti-aliasing filter (AAF) in the front-end of an analog-to-digital converter (ADC).
Mohsen Ghaemmaghami, Shahbaz Reyhani
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Novel Low-Power Mixed-Mode Universal Filter Design Using Multiple-Input Operational Transconductance Amplifiers

Technologies
This study introduces an innovative mixed-mode universal biquad filter implemented using multiple-input operational transconductance amplifiers (MI-OTAs).
Fabian Khateb, Pichai Suksaibul, Tomasz Kulej, Montree Kumngern   +3 more
doaj   +1 more source