Results 101 to 110 of about 461,179 (296)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
机车电传动, 2018 A high precision analog quantity input and output module for train control on-board equipment was elaborated, which was mainly composed of analog quantity input circuit, analog quantity output circuit, fault free output circuit, processing system and ...
TANG Ganglin, ZHAO Wenbin, ZHOU Xuedong
doaj
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Error Model of a Measurement Chain Containing the Discrete Wavelet Transform Algorithm
Applied SciencesThis paper presents an error model of a measurement chain containing a link that executes a discrete wavelet transform algorithm, which is most often the last stage of measurement signal processing.
Marian Kampik +2 more
doaj +1 more source
Journal of Low Power Electronics and Applications, 2019 This discussion develops a theoretical analog architecture framework similar to the well developed digital architecture theory. Designing analog systems, whether small or large scale, must optimize their architectures for energy consumption.
Jennifer Hasler
doaj +1 more source
A Software Defined Radio Test-Bed for WLAN Front Ends [PDF]
, 2002 ¿In our Software Defined Radio (SDR) project we aim at combining two different types of standards, Bluetooth and HiperLAN/2 on one common flexible hardware platform.
Arkesteijn, Vincent +5 more
core +2 more sources
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Behavioral SciencesA proper time display format is essential for pilots to understand integrated meteorological radar information, thereby making informed flying decisions and steering clear of hazardous weather.
Bo Liu, Yunhe Wang, Yongxin Li
doaj +1 more source
Silicon photonics devices for integrated analog signal processing and sampling
Nanophotonics, 2014 Silicon photonics offers the possibility of a reduction in size weight and power for many optical systems, and could open up the ability to build optical systems with complexities that would otherwise be impossible to achieve.
Spector Steven, Sorace-Agaskar Cheryl
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source