Results 71 to 80 of about 461,179 (296)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Data reduction complex analog-to-digital data processing requirements for onsite test facilities [PDF]

The analog to digital processing requirements of onsite test facilities are described. The source and medium of all input data to the Data Reduction Complex (DRC) and the destination and medium of all output products of the analog-to-digital processing ...
Debbrecht, J. D.
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

5G Millimeter Wave Cellular System Capacity with Fully Digital Beamforming

, 2018
Due to heavy reliance of millimeter-wave (mmWave) wireless systems on directional links, Beamforming (BF) with high-dimensional arrays is essential for cellular systems in these frequencies. How to perform the array processing in a power efficient manner
Barati, C. Nicolas, Dhananjay, Aditya, Dutta, Sourjya, Rangan, Sundeep   +3 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Microwave signal processing using an analog quantum reservoir computer

Nature Communications
Quantum reservoir computing (QRC) has been proposed as a paradigm for performing machine learning with quantum processors where the training takes place in the classical domain, avoiding the issue of barren plateaus in parameterized-circuit quantum ...
Alen Senanian, Sridhar Prabhu, Vladimir Kremenetski, Saswata Roy, Yingkang Cao, Jeremy Kline, Tatsuhiro Onodera, Logan G. Wright, Xiaodi Wu, Valla Fatemi, Peter L. McMahon   +10 more
doaj   +1 more source

System architecture study of an orbital GPS user terminal [PDF]

The generic RF and applications processing requirements for a GPS orbital navigator are considered. A line of demarcation between dedicated analog hardware, and software/processor implementation, maximizing the latter is discussed.
Martin, D. P., Neily, C. M., Jr.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Digital Signal Processing Over Analog Signal Processing

Journal of Advance Research in Electrical & Electronics Engineering (ISSN: 2208-2395), 2014
This paper provides a survey of digital signal processing over analog signal processing. Initially digital signal processing is developed to replace limited application based analog signal processing (ASP) of high cost. This paper describes the comparison of analog signal processing (ASP) and digital signal processing, technology under digital signal ...
Sushma Sharma, Hitesh Kumar, Charul Thareja   +2 more
openaire   +2 more sources