Results 61 to 70 of about 4,799,373 (254)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Towards a Standard Mixed-Signal Parallel Processing Architecture for Miniature and Microrobotics
, 2014 The conventional analog-to-digital conversion (ADC) and digital signal processing (DSP) architecture has led to major advances in miniature and micro-systems technology over the past several decades.
Sadler, Brian M.; Hoyos, Sebastian
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Applications of a CMOS current squaring circuit in analog signal processing
, 2015 Minaei, Shahram (Dogus Author) -- Conference full title: 2015 38th International Conference on Telecommunications and Signal Processing, TSP 2015; Prague; Czech Republic; 9 July 2015 through 11 July 2015Applications of a CMOS squaring circuit in analog ...
Özoğuz, Serdar +6 more
core +1 more source
Advanced Photonics ResearchAnalog computing based on miniaturized surfaces has gained attention for its high‐speed and low‐power mathematical operations. Building on recent advances, an anisotropic space‐time digital metasurface for parallel and programmable wave‐based ...
Javad Shabanpour
doaj +1 more source
Low-Power, High-Speed Adder Circuit Utilizing Current-Starved Inverters in 22 nm FDSOI
ChipsA low-power, high-speed adder circuit topology based on current-starved inverters is presented to provide a basic arithmetic function for low-power, high-frequency signal processing systems. The adder is designed in 22 nm FDSOI (Fully-Depleted Silicon-on-
Jeff Dix
doaj +1 more source
Journal of Nanotechnology, 2018 Carbon nanotube (CNT) is one of the embryonic technologies within recent inventions towards miniaturization of semiconductor devices and is gaining much attention due to very high throughput and very extensive series of applications in various analog ...
Varsha S. Bendre +2 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source