Results 41 to 50 of about 283,015 (290)
MENGGALI KEARIFAN LOKAL MELALUI KAJIAN ETNOARKEOLOGI
Berkala Arkeologi, 2009 Local wisdom inherited by our ancestors has gradually been abandoned by present generation. Local wisdom actually taught us to live harmoniously with the surrounding environtment.
Gunadi Kasnowihardjo
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Connection Science, 2017 Concept blending – a cognitive process which allows for the combination of certain elements (and their relations) from originally distinct conceptual spaces into a new unified space combining these previously separate elements, and enables reasoning and ...
Tarek R. Besold +2 more
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The psychic life of freedom: Social pathology and its symptoms [PDF]
Filozofija i Društvo, 2017 This paper discusses the relationship between Axel Honneth’s intersubjective theory of recognition and his political theory of democratic ethical life by addressing the potentials and difficulties attached to the notion of social pathology ...
Bueno Arthur
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Concept commun et concept analogique de compromis : « un air de famille »
Sociologies, 2010 Should we consider the concept of compromise only in the presence of partners willing to negotiate and who both accept to make concessions in order to arrive at some form of agreement? Is it appropriate to talk of compromise when facing abstract entities
Mohamed Nachi
doaj
Topics in Cognitive Science, 2017 AbstractA central question in human development is how young children gain knowledge so fast. We propose that analogical generalization drives much of this early learning and allows children to generate new abstractions from experience. In this paper, we review evidence for analogical generalization in both children and adults.
Dedre Gentner, Christian Hoyos
openaire +2 more sources
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source