Results 71 to 80 of about 1,342,850 (388)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Gradability and Knowledge [PDF]
, 2017 Epistemic contextualism (‘EC’), the view that the truth-values of knowledge attributions may vary with the context of ascription, has a variety of different linguistic implementations.
Michael, Blome-Tillmann
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Non-global jet evolution at finite N_c
, 2003 Resummations of soft gluon emissions play an important role in many applications of QCD, among them jet observables and small x saturation effects.
Balitsky +22 more
core +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Illuminating Causality: The Role of Light in Thomas Aquinas’s Metaphysics of Being
ReligionsIn this article, we hold a strong thesis, i.e., that light is the conceptual resource that best explains the creative act in Thomas Aquinas’s metaphysics.
Jorge Eduardo Arbeláez +1 more
doaj +1 more source
Złożenia w rosyjskim slangu młodzieżowym
Studia Rossica Posnaniensia, 2018 The article is devoted to compounds in Russian youth slang. The author proves that young people treat compounds as a basis for creative modifications and play with words by combining various parts of speech, different styles, languages in one in order to
Katarzyna Kubecka
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Bylocks Drakskeppstrilogi – analogi och kulturmöten
Barnboken: Tidskrift för Barnlitteraturforskning, 2011 In my thesis “It could just as well have happened today”: Maj Bylock's Drakskeppstrilogi and historical consciousness in ten- to twelve-year-olds, I provide a textual, thematic analysis of the three novels from 1997–1998. Further, in an empirical study I
Ingemansson, Mary
doaj
Journal Of Babylon Center For Humanities Studies, 2021 The aim of this research is to study Alakhfash's Grammar Analogy, who whose opinions have been affected both the advanced and late grammarians. The importance of this research is to follow the issues that are unique to Alakhfash in analogy, study them ...
انتصار تاج السر العوض عبدالرحمن Entisar Tagelsir Elawad Abdelrahman
doaj
Analogous: Digital / Analogue Metaphors. [PDF]
, 2011 When discussing our understanding of the world, the term ‘analogue’ has become shorthand for anything not digital, and has become an analogy of its own. ‘Digital’ has also become an analogy for anything requiring a computer.
Carpenter, Ele
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