Results 131 to 140 of about 2,686,830 (291)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Was lebt denn da? Mikroben in mittelalterlichen Handschriften
Library Ideas, 2020 Katharina Therese Gietkowski
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Analyse Longitudinale Des Ide En Algérie
المجلة الدولية للأداء الاقتصادي, 2018 يعتبر الاستثمار الأجنبي المباشر عنصرا أساسيا في استراتيجية الانتعاش الاقتصادي ،لأنه بفضله يمكن دفع عجلة النمو التي يؤدي زيادة في الإنتاجية من جهة و في التنويع الاقتصادي من جهة أخرى و كذلك في زيادة مقاومة الصدمات الخارجية.
Abdelmadjid Ounis , Hadjira CHIGARA
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
, 2013 Rapporten er en analyse av data fra tre av Utdanningsdirektoratets brukerundersøkelser i skolen. Dette er Elevundersøkelsen, Lærerundersøkelsen og Foreldreundersøkelsen. Oppdragsgiver er Utdanningsdirektoratet. Et overordnet mål for oppdragsgiver er å få
Wendelborg, Christian +1 more
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
, 2009 ANALYSE Vorbereitende Untersuchung Müllerstraße (Rights reserved) (-) Ausgabe 2009 Analyse (Rights reserved) (-
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Téoros, 2007 Le mont Tremblant, situé dans les Laurentides au Québec, est une des destinations touristiques parmi les plus attractives du Canada, voire de l’Amérique du Nord, tant pour les vertus de son paysage « naturel » que ses qualités récréatives.
Fabienne Joliet, Thibault Martin
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