Results 151 to 160 of about 2,686,830 (291)
Die literaturwissenschaftliche Rezeptionstheorie untersucht die Beziehungen und Determinationsfaktoren im Verhältnis Text — Leser — Wirklichkeit.
Mayordomo, Moisés
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
[Genealogy, breeding and (bio)politics. The History of Knowledge and the Formation of Racial Discourse in the Early Modern and Modern Periods]. [PDF]
Lettow S.
europepmc +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Statistiske undersøkelser av spørsmål om mobbing : Analyse av Elevundersøkelsen våren 2015
-Dette notatet er en analyse av data av den frivillige gjennomføringen av Elevundersøkelsen som ble foretatt våren 2015. Analysene har som hensikt å undersøke om det er eventuelle metodiske effekter som kan forklare en betydelig nedgang i andelen elever ...
Wendelborg, Christian
core
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Analysing the implementation and transferability of an enhanced care pathway integrating systematic supportive cancer care and patient-partner support for people living with anal cancer: Protocol for a mixed-methods study in two French cancer centres. [PDF]
Carillon S +6 more
europepmc +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source

