Results 201 to 210 of about 8,998,975 (283)

Stability of Composite Plates with a Dense System of Ribs in Two Directions. [PDF]

Materials (Basel)
Marczak J, Rabenda M, Michalak B.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Bridging Science and Subjectivity: Evolving Evidence, Emerging Technologies and the Call for Personalised Psychotherapy: Créer une passerelle entre la science et la subjectivité : Évolution des données probantes, arrivée de nouvelles technologies et appel à une psychothérapie personnalisée. [PDF]

Can J Psychiatry
Khan N.
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

A comparative study of choroidal thickness and pigment epithelial detachment in acute and chronic central serous chorioretinopathy in Nepalese patients. [PDF]

PLoS One
Bhatta S, Pant N, Pant SR.
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Modelling of hybrid deep learning framework with recursive feature elimination for distributed denial of service attack detection systems. [PDF]

Sci Rep
Alkhliwi S.
europepmc   +1 more source

Dataset on thermophysical properties of natural stones for heat storage applications. [PDF]

Data Brief
Seyitini L, Belgasim B, Enweremadu CC.
europepmc   +1 more source

A comparative study of the injury patterns and inflammatory response between suicidal and unintentional falls from height in Germany. [PDF]

Eur J Trauma Emerg Surg
Zellner AA, Schmitt MR, Roos J, Prangenberg C, Pennig H, Cucchi D, Scheidt S.   +6 more
europepmc   +1 more source