Results 101 to 110 of about 69,874,824 (396)

Information Base of Formation of Alternative Variants of Management Decisions [PDF]

open access: yesBìznes Inform, 2018
The article describes the procedures for identification of the main problem, structuring and analyzing of problems of an organizational system in order to create an information base of the process of forming alternative managerial decisions. This base is
Suslov Oleg P.   +2 more
doaj  

Principal Component Analysis

open access: yesEncyclopedia of Machine Learning, 2003
Principal component analysis is one of the most important and powerful methods in chemometrics as well as in a wealth of other areas. This paper provides a description of how to understand, use, and interpret principal component analysis.
I. Jolliffe
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

From the Cover: Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

open access: yes, 2005
Although genomewide RNA expression analysis has become a routine tool in biomedical research, extracting biological insight from such information remains a major challenge.
A. Subramanian   +10 more
semanticscholar   +1 more source

MEGA6: Molecular Evolutionary Genetics Analysis version 6.0.

open access: yesMolecular biology and evolution, 2013
We announce the release of an advanced version of the Molecular Evolutionary Genetics Analysis (MEGA) software, which currently contains facilities for building sequence alignments, inferring phylogenetic histories, and conducting molecular evolutionary ...
K. Tamura   +4 more
semanticscholar   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

The current status of the Papuan pro-independence movement [PDF]

open access: yes
Examines the aims, capacity, leadership and activities of both the armed units of the Free Papua Organisation (Organisasi Papua Merdeka, OPM) and the various political groupings supporting independence in Papua and abroad. Executive summary Indonesia’s
Institute for Policy Analysis of Conflict
core  

Fall 2015 [PDF]

open access: yes, 2015
https://nsuworks.nova.edu/shss_dcar/1009/thumbnail ...
Department of Conflict Analysis and Resolution
core   +1 more source

BEAST 2: A Software Platform for Bayesian Evolutionary Analysis

open access: yesPLoS Comput. Biol., 2014
We present a new open source, extensible and flexible software platform for Bayesian evolutionary analysis called BEAST 2. This software platform is a re-design of the popular BEAST 1 platform to correct structural deficiencies that became evident as the
R. Bouckaert   +8 more
semanticscholar   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

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