Results 121 to 130 of about 27,676,138 (298)

COREnet: the fusion of social network analysis and target audience analysis [PDF]

open access: yes, 2014
The purpose of this capstone is to highlight and explain how the target audience analysis (TAA) process can be enhanced by incorporating aspects of influence theory, social movement theory (SMT) and social network analysis (SNA).
Orkins, William R., Kiernan, Carla A.
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Situational analysis of tobacco control in Kenya : report of the full analysis carried out by the Kenya Tobacco Control Situational Analysis Consortium

open access: yes, 2010
The table of contents for this item can be shared with the requester. The requester may then choose one chapter, up to 10% of the item, as per the Fair Dealing provision of the Canadian Copyright ActTobacco Production is labour intensive, leading to use ...
Kenya Tobacco Control Situational Analysis Consortium
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Analysis and selection of the structure of a multiprocessor computing system according to the performance criterion

open access: yesРоссийский технологический журнал
Objectives. Analysis of the various architectures of computing systems (CSs) used in recent decades has allowed us to identify the most common structures. One of the key features is the use of mass-produced equipment to create data processing subsystems (
G. V. Petushkov, A. S. Sigov
doaj   +1 more source

SNCOs: A Developmental Analysis [PDF]

open access: yes, 2018
Defense Analysis ...
Eudy, Alex
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Subject Analysis, Content Analysis and Domain Analysis

open access: yesThe Canadian Journal of Information and Library Science
From the perspective of the constant increase in data and information, consider in Library and Information Science that the correct analysis and representation of the contents of documents analyzed in specific domains is essential for the retrieval, organization, and dissemination of information.
Alves Silva Portella, Tauany Lorena   +1 more
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy