Results 141 to 150 of about 27,676,138 (298)
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The history of arising and development of the concept of «startup company» have been studied and the importance of their activities have been determined.
S.F. Legenchuk, G.V. Pilipchuk
doaj
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Quarterly Market Analysis Report April-June 2020
A quarterly Market Analysis Report April – June 2020This is a quarterly market analysis report prepared by The Kenya Institute for Public Policy Research and Analysis on the performance of the Financial market of Kenya.
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A RE-ANALYSIS OF CONFLUENCE ANALYSIS *
Hendry, David F, Morgan, Mary S
openaire +3 more sources
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Australia in a century of transformative governance: a federation for communities and places
This paper has been commissioned by Local Government Professionals Australia as a contribution to debate on the future of the Australian federation and as a response to the National Innovation and Science agenda.
Local Government Professionals Australia +1 more
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Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Quarterly Market Analysis Report January-March 2020
A quarterly Market Analysis Report January – March 2020This is a quarterly market analysis report prepared by The Kenya Institute for Public Policy Research and Analysis on the performance of the Financial market of Kenya. The report focuses on different
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