Results 141 to 150 of about 27,676,138 (298)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Historical aspects of arising and features of activity of startup companies: accounting and economic aspects

open access: yesПроблеми теорії та методології бухгалтерського обліку, контролю і аналізу, 2016
The history of arising and development of the concept of «startup company» have been studied and the importance of their activities have been determined.
S.F. Legenchuk, G.V. Pilipchuk
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Quarterly Market Analysis Report April-June 2020

open access: yes, 2020
A quarterly Market Analysis Report April – June 2020This is a quarterly market analysis report prepared by The Kenya Institute for Public Policy Research and Analysis on the performance of the Financial market of Kenya.

core  

A RE-ANALYSIS OF CONFLUENCE ANALYSIS *

open access: yesOxford Economic Papers, 1989
Hendry, David F, Morgan, Mary S
openaire   +3 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Australia in a century of transformative governance: a federation for communities and places

open access: yes, 2016
This paper has been commissioned by Local Government Professionals Australia as a contribution to debate on the future of the Australian federation and as a response to the National Innovation and Science agenda.
Local Government Professionals Australia   +1 more
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Quarterly Market Analysis Report January-March 2020

open access: yes, 2020
A quarterly Market Analysis Report January – March 2020This is a quarterly market analysis report prepared by The Kenya Institute for Public Policy Research and Analysis on the performance of the Financial market of Kenya. The report focuses on different

core  

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