Results 211 to 220 of about 48,044,330 (330)

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Immune cell dynamics and prognostic role of M2 macrophages and LDOC1 in colon adenocarcinoma. [PDF]

Discov Oncol
Luo L, Xu Z, Lin H, Huang R.
europepmc   +1 more source

The Analysis of Proteins. II. The Action of Nitrous Acid upon the Hexone Bases [PDF]

, 1924
Robert Henry Aders Plimmer
openalex   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Genome-wide analysis identifies susceptibility loci for heart failure and nonischemic cardiomyopathy subtype in the East Asian populations. [PDF]

PLoS Genet
Han Y, Hong Y, Gao Y, Lu J, Chen B, Zhang L, Yan X, Sun Y, Zhang L, Liu J, Dai H, Hou L, Li X, Li J.   +13 more
europepmc   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

ANALYSIS OF MARKETING RESEARCH [PDF]

, 2013
Torba, M.
core  

Identification of biomarkers associated with glycolysis and lactation in sarcopenia. [PDF]

Sci Rep
Luo X, Liu J, Luo X, Li Y, Chen Q, He Z, Lei Y, Li S, Wang X, Jiang J, Yang Z, Yang L.   +11 more
europepmc   +1 more source

THE COMPOSITION OF THE ADULT HUMAN BODY AS DETERMINED BY CHEMICAL ANALYSIS

, 1953
Richard Forbes, A.R. Cooper, H.H. Mitchell   +2 more
openalex   +1 more source

A Text-Book of Qualitative Chemical Analysis [PDF]

, 1941
E. F. ARMSTRONG
openalex   +1 more source