Results 91 to 100 of about 1,366,341 (295)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Marked and the Magic in \u3cem\u3eProspero’s Daughter\u3c/em\u3e: Contextualizing Postmodern Witchcraft Accusations Using the Early Modern [PDF]
Despite Prospero’s Daughter having won Elizabeth Nunez a handful of awards and having been received positively by critics, little aside from reviews about the novel exists in the literary sphere.
Gomez, Olivia
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Feminists feel that in literary criticism not enough consideration is given to feminism as an ideology in the production of texts. According to them, existing literary criticism is strongly man-centred.
J. W. du Plessis, D. H. Steenberg
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Analisis Isnad Cum Matn: Mengukur Kritik Hadis Muslim Dan Barat
Islamic scholars have built the method of hadith criticism since the early times to determine the validity of a hadith. Similarly, the West has for long developed its own methods in contrast to hadith criticism by the Muslim scholars.
Maizuddin M. Nur
doaj +1 more source
What is wrong with consumerism [PDF]
Contemporary consumerism is frequently the target of criticisms by intellectuals, academics, religious spokesmen and commentators. Five of the more common of these criticisms are selected for analysis and examination; these being (a) the need ...
Campbell, C. (Colin)
core

