Results 91 to 100 of about 206,415 (298)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
TOWARDS A CRITICISM OF THE BODY IN MUSIC: RECOGNIZING AND REVERSING THE MIND-BODY SPLIT IN TRADITIONAL SCHOLARSHIP [PDF]
, 2001 Since antiquity, the study of Western classical music has been influenced by widespread beliefs in the mind-body split. Rational and idealistic philosophies, such as those expounded by Descartes and Plato, have led prominent music scholars throughout ...
Ramunno, Sandra
core +1 more source
The critic as transvestite: the parody nature of literary criticism
Estudios de Teoría Literaria, 2016 This paper explores a path in the analysis of literary criticism as an object of study. In order to convey this, this essay attempts to define literary criticism as a genre that parodies the literary text it aspires to examine. Mikhail Bakhtin’s analysis
David Pruneda Sentíes
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Model Criticism in Latent Space [PDF]
, 2019 Model criticism is usually carried out by assessing if replicated data generated under the fitted model looks similar to the observed data, see e.g. Gelman, Carlin, Stern, and Rubin (2004, p. 165).
Seth, Sohan +4 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
MANHAJ KRITIK MATAN ‘Ā’ISYAH RA
Muwazah, 2013 This paper discussed the methods used by ‘Ā’isyah as benchmark in criticizing matan hadith. The accusation against Islam about the lack of methodology in the study of hadith criticism, especially matan criticism, has forced contemporary Islamic scholars ...
Niki Alma Febriana Fauzi
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
The development and validation of the child self-criticism scale (CSCS) [PDF]
Social and competitive environmental pressures, combined with changes in self-identity, make self-criticism especially problematic in the identity-forming phase of childhood. Yet, no robust measure of self-criticism exists for use with child populations.
Stupple, E. +3 more
core +1 more source