Results 81 to 90 of about 206,415 (298)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
As Julian Horton's provocative discussion of the tension between modern methodologies of interpretatio n and the traditional claims of analysis suggests, writing about music is a frustrating enterprise. To a great extent, the difficulty arises from the performative nature of music as well as from the inherent ambiguity of music's meaning.
openaire +1 more source
19th CENTURY MUSIC CRITICISM AND AESTHETICS: MUTUAL INFLUENCES
During the 19th century, due to cultural, economical and social conditions, there were significant changes in the direction and the aesthetic status of music.
Irina, Mihaela
core +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
This article describes attempts that cross-fertilize spatial science and critical geographies and challenge the analytical/quantitative versus critical/qualitative distinction existing across human geography. The article is organized on the basis of criticisms of positivist quantitative geography; it discusses both (early) attempts to articulate the ...
openaire +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Toward a Geography of Architectural Criticism: Disciplinary Boundaries and Shared Territories (3)
Geoffrey Scott’s The Architecture of Humanism at the Inception of Bruno Zevi’s Theoretical Corpus Raúl Martínez Martínez Department of History and Theory of Architecture, Universitat Politècnica de Catalunya-BarcelonaTech By the late nineteenth century,
Mapping Architectural Criticism
core
The development of the Japanese version of the Forms of Self-Criticising/Attacking & Self-Reassuring Scale (J-FSCRS): implications for cross-cultural research on self-criticism and self-reassurance [PDF]
People with high self-criticism tend to suffer from poor mental health whereas those with high self-reassurance tend to have good mental health. Poor mental health is a great cause for concern in Japan. Many people in Japan live with mental health issues,
Kotera, Yasuhiro +13 more
core +1 more source

