Results 61 to 70 of about 482,820 (312)

Numerical analysis of the load bearing capacity of pin-ended hybrid headed columns under uniaxial loading [PDF]

open access: yes, 2011
The behaviour of fully encased composite columns loaded in axial compression through the concrete core and whole cross-section was studied. The primary objective is to develop a complete non-linear finite element model that could represent the behaviour ...
Abdulhaq, Ahmed   +2 more
core   +1 more source

Bending Stiffness, Load-Bearing Capacity and Flexural Rigidity of Slender Hybrid Wood-Based Beams

open access: yesForests, 2018
Modern architecture suggests the use of opened spaces with large transparent envelope surfaces. Therefore, windows of long widths and large heights are needed.
B. Šubic, G. Fajdiga, J. Lopatic
semanticscholar   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Direct method-based statistical limit analysis of wc-co composites [PDF]

open access: yes, 2013
In this paper, a direct method-based prediction of load-bearing capacity of nonperiodic WC-Co composites is presented. The main goal is to generalize the methodology of limit analysis on periodic heterogeneous media to materials with random ...
Chen, Geng   +2 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Prediction of vertical bearing capacity of waveform micropile [PDF]

open access: yes, 2019
This study proposes a predictive equation for bearing capacity considering the behaviour characteristics of a waveform micropile that can enhance the bearing capacity of a conventional micropile.
Han, J.-T.   +3 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

FEA of SFRC three ribbed wall panel / Azrul Md Din [PDF]

open access: yes, 2014
This finite element study was carried out to investigate the steel fibre reinforced concrete with three (3) ribbed wall (SFRC-3RW) panel containing reinforced wire mesh (BRC) subjected to axial and eccentric loading also its load bearing response ...
Md Din, Azrul
core  

Load-Bearing Capacity and Fracture Behavior of Glass Fiber-Reinforced Composite Cranioplasty Implants

open access: yesJournal of Applied Biomaterials & Functional Materials, 2017
Background Glass fiber-reinforced composites (FRCs) have been adapted for routine clinical use in various dental restorations and are presently also used in cranial implants. The aim of this study was to measure the load-bearing capacity and failure type
J. Piitulainen   +3 more
semanticscholar   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

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