Results 71 to 80 of about 54,461 (266)

Load Capacity Analysis of Step Thrust Bearing based on CFD

Jixie chuandong, 2018
On the basis of liquid cavitation two-phase flow theory of hydrodynamic lubrication,the hydrodynamic lubrication model of the step thrust bearing is analyzed by means of computational fluid dynamics（ CFD） simulation,which is based on the numerical ...
Zhang Wentao, Zhang Zhixin
doaj  

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Optimization of Structural Configuration and Ridge Height for Large-Span Insulated Plastic Greenhouse Based on Finite Element Analysis

Agriculture
The large-span insulated plastic greenhouse is a highly promising horticultural facility. The design parameters and configuration of structural components significantly impact their safety and load-bearing performance.
Xiaoxing Dong, Fengzhi Piao, Nanshan Du, Han Dong, Tao Zhang, Yanping Qin, Yaling Li, Zhixin Guo   +7 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Soil Compaction and Classification Analysis for Enhanced Load-Bearing Capacity in Construction

European Journal of Theoretical and Applied Sciences
Soil compaction represents a critical construction procedure that ensures the stability and load-bearing capacity of foundations, particularly in regions characterized by heterogeneous soil properties. This study addresses the paucity of soil compaction data in Khuzdar, Balochistan, by examining the compaction characteristics and classification of soil
Mst Julia, Akter, Muhammad, Aslam, Asad, Manan, Muhammad, Asif, Syed Zakir Ali, Shah, Ali, Hassan   +5 more
openaire   +2 more sources

Degradation analysis of concrete bridge load-bearing capacity based on crack distribution

Journal of Highway and Transportation Research and Development (English Edition)
In-service reinforced concrete bridges, following prolonged operational periods, frequently undergo alterations in structural integrity and significant deterioration of material properties. As a result, it becomes imperative to evaluate and analyze these bridge structures.
Zhirong Ma, Xiaoguang Wu, Xingke Chang, Jiang Huang   +3 more
openaire   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Study on increasing load capacity of wooden arch bridge by CFRP strengthening: experimental and numerical Verification

Frontiers in Materials
The wooden arch corridor bridge is a typical representative of Chinese wooden bridges, holding significant historical research value. Currently, these bridges face issues of severe component deformation and insufficient load-bearing capacity.
Liping Li, Yan Wang, Yafei Zhang, Xu Wang, Guangyao Ji, Xuping Li   +5 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Bearing behavior of pile foundation in karst region: Physical model test and finite element analysis

Applied Rheology
The presence of karst formations significantly impacts the load-bearing capacity of pile foundations in karst geological environments, posing a challenge to their design. This study investigated the bearing characteristics of karst pile foundations using
Sheng Minghong, Lu Fangqing, Jiang Nan, Guo Panpan, Li Xian, An Ran, Wang Yixian   +6 more
doaj   +1 more source