Results 91 to 100 of about 818,608 (269)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Analytic analysis of algorithms
, 1992 The average case analysis of algorithms can avail itself of the development of synthetic methods in combinatorial enumerations and in asymptotic analysis. Symbolic methods in combinatorial analysis permit to express directly the counting generating functions of wide classes of combinatorial structures.
openaire +2 more sources
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Time series big data: a survey on data stream frameworks, analysis and algorithms. [PDF]
J Big Data, 2023 Almeida A +3 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
An assessment tool for computer-assisted semen analysis (CASA) algorithms. [PDF]
Sci Rep, 2022 Choi JW +5 more
europepmc +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Statistical Testing of Segment Homogeneity in Classification of Piecewise–Regular Objects
International Journal of Applied Mathematics and Computer Science, 2015 The paper is focused on the problem of multi-class classification of composite (piecewise-regular) objects (e.g., speech signals, complex images, etc.).
Savchenko Andrey V., Belova Natalya S.
doaj +1 more source
Fourier Analysis of Genetic Algorithms
Theoretical Computer Science, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Walter A. Kosters +2 more
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source