Results 121 to 130 of about 1,094,599 (317)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Hybrid Newton-like Inverse Free Algorithms for Solving Nonlinear Equations

open access: yes
Iterative algorithms requiring the computationally expensive in general inversion of linear operators are difficult to implement. This is the reason why hybrid Newton-like algorithms without inverses are developed in this paper to solve Banach space ...
Argyros, Christopher I.   +7 more
core   +1 more source

Theoretical analysis of steady state genetic algorithms [PDF]

open access: yes, 2014
summary:Evolutionary Algorithms, also known as Genetic Algorithms in a former terminology, are probabilistic algorithms for optimization, which mimic operators from natural selection and genetics.
Agapie, Alexandru   +3 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Time integration algorithms for finite element analysis of creep problems

open access: yes, 1989
Bibliography: leaves 127-132.The fundamental principles involved in the selection and implementation of time integration schemes for finite element analysis of nonlinear creep problems are investigated.
Marais, Nicholas John
core  

An assessment tool for computer-assisted semen analysis (CASA) algorithms. [PDF]

open access: yesSci Rep, 2022
Choi JW   +5 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Statistical Testing of Segment Homogeneity in Classification of Piecewise–Regular Objects

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2015
The paper is focused on the problem of multi-class classification of composite (piecewise-regular) objects (e.g., speech signals, complex images, etc.).
Savchenko Andrey V., Belova Natalya S.
doaj   +1 more source

Fourier Analysis of Genetic Algorithms

open access: yesTheoretical Computer Science, 1999
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Walter A. Kosters   +2 more
openaire   +1 more source

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