Results 51 to 60 of about 163,989 (311)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Numerical evidence for phase transitions of NP-complete problems for instances drawn from Lévy-stable distributions [PDF]

open access: yes, 2011
Random NP-Complete problems have come under study as an important tool used in the analysis of optimization algorithms and help in our understanding of how to properly address issues of computational intractability.
Connelly, Abram, Abram Connelly
core   +1 more source

Fifty years of scheduling: a survey of milestones [PDF]

open access: yes, 2009
Scheduling has become a major field within operational research with several hundred publications appearing each year. This paper explores the historical development of the subject since the mid 1950s when the landmark publications started to appear.
Strusevich, Vitaly A.   +5 more
core   +1 more source

B-Tree Algorithm Complexity Analysis to Evaluate the Feasibility of its Application in the University Course Timetabling Problem [PDF]

open access: yesJournal of Artificial Intelligence and Soft Computing Research, 2013
Abstract This paper presents a comparative analysis of complexity between the B-TREE and the Binary Search Algorithms, both theoretically and experimentally, to evaluate their efficiency in finding overlap of classes for students and teachers in the University Course Timetabling Problem (UCTP).
Marco Antonio Cruz Chvez   +1 more
openaire   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

On the probabilistic min spanning tree Problem [PDF]

open access: yes, 2010
International audienceWe study a probabilistic optimization model for min spanning tree, where any vertex v i of the input-graph G(V, E) has some presence probability p i in the final instance G′ ⊂ G that will effectively be optimized.
Paschos, V.T.   +10 more
core   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Complexity analysis of primal-dual algorithms for the semidefinite linear complementarity problem

open access: yesJournal of Numerical Analysis and Approximation Theory, 2011
In this paper a primal-dual path-following interior-point algorithm for the monotone semidefinite linear complementarity problem is presented. The algorithm is based on Nesterov-Todd search directions and on a suitable proximity for tracing approximately the central-path.
Mohamed Achache, Naima Boudiaf
openaire   +3 more sources

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Revisiting Online Algorithms: A Survey of Set Cover Solutions Beyond Competitive Analysis

open access: yesIEEE Access
Online algorithms are crucial for real-time decision-making and adaptability across diverse fields, such as operations research, computer science, and combinatorics. These algorithms handle data incrementally and make decisions without prior knowledge of
Christine Markarian   +2 more
doaj   +1 more source

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