Analysis of brain structural covariance network in Cushing disease
Background: Cushing disease (CD) is a rare clinical neuroendocrine disease. CD is characterized by abnormal hypercortisolism induced by a pituitary adenoma with the secretion of adrenocorticotropic hormone.
Can-Xin Xu +7 more
doaj +1 more source
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li +6 more
wiley +1 more source
Novel Process Noise Model for GNSS Kalman Filter Based on Sensitivity Analysis of Covariance with Poor Satellite Geometry. [PDF]
Takayama Y, Urakubo T, Tamaki H.
europepmc +1 more source
Assessing Strengths and Limitations of Magnetoencephalography Source Imaging With Intracerebral EEG
Simultaneous MEG and stereotactic EEG (SEEG) recordings provide a direct validation framework for MEG source imaging in focal epilepsy. Virtual SEEG signals derived from MEG reconstructions reveal significant agreement with intracranial measures of spike localization, resting‐state oscillations, and functional connectivity, while also identifying ...
Jawata Afnan +10 more
wiley +1 more source
Towards Analysis of Covariance Descriptors via Bures–Wasserstein Distance
A brain–computer interface (BCI) provides a direct communication pathway between the human brain and external devices, enabling users to control them through thought.
Huajun Huang +4 more
doaj +1 more source
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo +18 more
wiley +1 more source
The Effects of Data Imputation on Covariance and Inverse Covariance Matrix Estimation
Various data analysis techniques and procedures (correlation heatmap, linear discriminant analysis, quadratic discriminant analysis) rely on the estimation of the covariance matrix or its inverse (the precision matrix).
Tuan L. Vo +5 more
doaj +1 more source
Comprehensive assessment of alterations in hand deformities over 11 years in patients with rheumatoid arthritis using cluster analysis and analysis of covariance. [PDF]
Toyama S +6 more
europepmc +1 more source
StackingNet: Collective Inference Across Independent AI Foundation Models
ABSTRACT Artificial intelligence (AI) built on large foundation models has transformed language understanding, computer vision, and reasoning, yet these systems remain isolated and cannot readily share their capabilities. Coordinating the complementary strengths of independently developed, black‐box foundation models is essential for trustworthy ...
Siyang Li +4 more
wiley +1 more source
Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations
Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford +3 more
wiley +1 more source

