Results 171 to 180 of about 173,975,381 (346)

Polyphyllin I Alleviates Alcoholic Liver Disease via Modulation of the Phosphodiesterase 6D–Cyclic Guanosine Monophosphate–Protein Kinase G Axis

Phytotherapy Research, EarlyView.
ABSTRACT Alcoholic liver disease (ALD) is a multifaceted disorder in which oxidative injury, iron‐dependent ferroptosis, steatosis, and inflammation are closely intertwined. Consequently, therapeutic strategies targeting a single pathway often produce limited clinical benefits.
Hongyan Feng, Xuelian Yuan, Yawen Xie, Zhenni Xia, Zhaohui Guo, Xuesong Liu, Rong Li, Wenliang Wang   +7 more
wiley   +1 more source

Adaptive Sliding‐Mode Control of a Perturbed Diffusion Process With Pointwise In‐Domain Actuation

International Journal of Robust and Nonlinear Control, EarlyView.
ABSTRACT A sliding mode–based adaptive control law is proposed for a class of diffusion processes featuring a spatially‐varying uncertain diffusivity and equipped with several point‐wise actuators located at the two boundaries of the spatial domain as well as in its interior.
Paul Mayr, Alessandro Pisano, Stefan Koch, Markus Reichhartinger   +3 more
wiley   +1 more source

A PDES method preserving boundaries on dense disparity map reconstruction

, 2008
Over smoothness restricts the application of PDEs in the field of dense disparity map reconstruction, because disparity map reconstruction usually requires preserving discontinuousness in some areas such as the boundaries of objects.
Liu J(刘霁), Wang YC(王越超), Peng JJ(彭军舰), Tang YD(唐延东)   +3 more
core   +1 more source

Convergence analysis of a Magnus-Rosenbrock type method for semilinear non-autonomous parabolic PDEs

Mukam JD, Tambue A. Convergence analysis of a Magnus-Rosenbrock type method for semilinear non-autonomous parabolic PDEs. Journal of Computational and Applied Mathematics. 2026;473: 116871.This paper investigates the time discretization of non-autonomous
Mukam, Jean Daniel, Tambue, Antoine
core   +1 more source

Artificial Intelligence for Blue Transformation: A Review of Predictive Modeling and Decision Support Systems in Sustainable Aquaculture

Sustainable Development, EarlyView.
ABSTRACT The FAO's “blue transformation” roadmap necessitates a fundamental shift towards precision aquaculture to meet global food security targets while minimizing environmental footprints. This review provides a comprehensive overview of how artificial intelligence (AI) and decision support systems (DSS) serve as pivotal enablers for the “better ...
Mustafa Öz, Enes Üstüner
wiley   +1 more source

Single‐Vesicle Functional Nanophenotyping Reveals Heterogeneous PD‐L1 Accessibility in Triple‐Negative Breast Cancer

Small Methods, EarlyView.
Graphical Abstract. High‐speed atomic force microscopy enables real‐time, label‐free visualization of antibody interactions with individual extracellular vesicles. By quantifying binding frequency and dwell time, this approach reveals functional PD‐L1 accessibility that cannot be inferred from protein abundance alone, uncovering nanoscale heterogeneity
Reon Imakawa, Keesiang Lim, Takeshi Yoshida, Tomoyoshi Yamano, Tsunaki Hongu, Uryo Onishi, Masaharu Hazawa, Toshio Ando, Noriko Gotoh, Rikinari Hanayama, Richard W. Wong   +10 more
wiley   +1 more source

The efficacy of phosphodiesterase‐5 inhibitors for erectile dysfunction in patients with post‐traumatic stress disorder and spinal cord injury: A systematic review and meta‐analysis

UroPrecision, EarlyView.
Abstract Erectile dysfunction (ED) is highly prevalent in men with post‐traumatic stress disorder (PTSD) and spinal cord injury (SCI), worsening psychological burden and quality of life. Phosphodiesterase‐5 (PDE‐5) inhibitors are established first‐line therapy for ED, but their efficacy in these specific populations has not been rigorously synthesized.
Yaser M. Ata, Mansoor Saleh, Esra Ata, Fatima Al‐Jassim, Omar Aboumarzouk   +4 more
wiley   +1 more source

Treatment Patterns and Pathways of Systemic Drug Therapy in Patients With Plaque, Erythrodermic, and Generalized Pustular Psoriasis: A Retrospective Cohort Study in Japan

The Journal of Dermatology, EarlyView.
ABSTRACT Systemic psoriasis treatment options have rapidly expanded in Japan, including the approval of tyrosine kinase 2 and interleukin‐36 receptor inhibitors in 2022. However, contemporary real‐world treatment patterns across plaque, erythrodermic, and generalized pustular psoriasis remain incompletely characterized.
Yayoi Tada, Yoshiko Maeda, Miyuki Hasegawa, Motonobu Sakaguchi, Takamasa Hashimoto, Teruko Narusawa, Nobuyoshi Takabayashi, Tomoko Takahashi, Taisuke Kondo, Shingo Kuroda   +9 more
wiley   +1 more source

Existence of quasi-periodic solutions for nonlinear evolution equations via the theorem of Nash-Moser

, 2012
We survey new existence and stability results of quasi-periodic solutions for ...
BERTI, MASSIMILIANO
core  

Systemic Treatment of Psoriasis: Current Evidence on Efficacy and Safety

The Journal of Dermatology, EarlyView.
ABSTRACT Systemic treatments for moderate‐to‐severe plaque psoriasis have been advanced from broad immunosuppressants up to agents more selectively targeting cytokines, cytokine receptors, or intracellular signaling. The current systemic treatments mainly consist of conventional systemic agents, biologics targeting tumor necrosis factor (TNF)‐α ...
Teppei Hagino, Naoko Kanda
wiley   +1 more source