Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Negative variance estimates in panel data models [PDF]
Negative values for estimated variances can arise in a panel data context. Empirical and theoretical literature dismisses the problem as not serious and a practical solution is to replace negative variances by its boundary value, i.e. zero. While this is
Laura Magazzini, Giorgio Calzolari
core
Regional Expression of Vimentin, S100, and Epithelial Membrane Antigen in the Human Medial Collateral Ligament: A Robust Two-Way Analysis of Variance. [PDF]
Stamenov N +9 more
europepmc +1 more source
Examining Side Effect Variability of Antipsychotic Treatment in Schizophrenia Spectrum Disorders: A Meta-analysis of Variance. [PDF]
Neumeier MS +7 more
europepmc +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Analysis of interaction effect between within- and between-subject factors in repeated measures analysis of variance for longitudinal data. [PDF]
Kim J, Park JH, Kim TK.
europepmc +1 more source
Raw Cow Milk Protein Stability under Natural and Technological Conditions of Environment by Analysis of Variance. [PDF]
Hanuš O +10 more
europepmc +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Avaliou-se a distribuição antropométrica da gordura abdominal em uma população adulta e o efeito de variáveis sócio-demográficas, reprodutivas e comportamentais sobre essa distribuição.
Marcelo Castanheira +2 more
doaj
A sensitivity study of urbanization impacts on regional meteorology using a Bayesian functional analysis of variance. [PDF]
Moraglia G, Bonas M, Crippa P.
europepmc +1 more source

