Results 131 to 140 of about 4,873,644 (382)
Boundary Behavior of Generalized Analytic Functions [PDF]
Kenneth A. Hoffman
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The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson+7 more
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Analytic transformations of everywhere dense point sets [PDF]
Philip Franklin
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Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli+10 more
wiley +1 more source
In this article, through the application of the q-Sălăgean operator associated with functions characterized by bounded boundary rotation, we propose a few new subclasses of bi-univalent functions that utilize the q-Sălăgean operator with bounded boundary
Prathviraj Sharma+3 more
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Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases
FEBS Letters, EarlyView.
Igor Zivkovic+2 more
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Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen+2 more
wiley +1 more source
The research group for analytical and bioanalytical sciences at the Department of Chemistry of the University of Basel is working on miniaturization of analytical techniques, with special focus on detection. Downsizing is a challenge for quantitation and contributions have been made based on different techniques which encompass atomic and ...
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On the Periodic Analytic Continuations of the Circular Orbits in the Restricted Problem of Three Bodies [PDF]
Aurel Wintner
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