Results 121 to 130 of about 2,072 (306)
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Machine learning (ML) of kinetic energy functionals (KEF) for orbital-free density functional theory (DFT) holds the promise of addressing an important bottleneck in large-scale ab initio materials modeling where sufficiently accurate analytic KEFs are ...
Sergei Manzhos +3 more
doaj +1 more source
Translation Theorem for Conditional Function Space Integrals and Applications
The conditional Feynman integral provides solutions to integral equations equivalent to heat and Schrödinger equations. The Cameron–Martin translation theorem illustrates how the Wiener measure changes under translation via Cameron–Martin space elements ...
Sang Kil Shim, Jae Gil Choi
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Approximate Functionals for Multistate Density Functional Theory [PDF]
Recently Lu and Gao [J. Phys. Chem. Lett. 13, 33, 7762-7769 (2022)] published a new, rigorous density functional theory for excited states and proved that the projection of the kinetic and electron repulsion operators into the subspace of the lowest ...
Alexander, Humeniuk
core +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Weierstrass Analytic Functions
Weierstrass introduced a complete analytic function as a set consisting of a power series and all its analytic continuations. This definition — a fundamental expansion of Lagrange’s introduction of a function as a power series — was formany decades the only alternative to the classical introduction of functions as laws or rules associating or pairing ...
openaire +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Reconstruction of linear functionals on classes of analytic functions of two variables on the basis of generalized information [PDF]
Для класів аналітичних функцій, означених за допомогою 2-вимірної композиції Адамара, запропоновано метод відновлення лінійних функціоналів на основі блендінгових конструкцій; вказані найкращі методи відновлення, знайдені точні оцінки похибки.For ...
Вакарчук, С.Б.
core

