Results 121 to 130 of about 2,072 (306)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Machine learning-guided construction of an analytic kinetic energy functional for orbital free density functional theory

open access: yesMachine Learning: Science and Technology
Machine learning (ML) of kinetic energy functionals (KEF) for orbital-free density functional theory (DFT) holds the promise of addressing an important bottleneck in large-scale ab initio materials modeling where sufficiently accurate analytic KEFs are ...
Sergei Manzhos   +3 more
doaj   +1 more source

Translation Theorem for Conditional Function Space Integrals and Applications

open access: yesMathematics
The conditional Feynman integral provides solutions to integral equations equivalent to heat and Schrödinger equations. The Cameron–Martin translation theorem illustrates how the Wiener measure changes under translation via Cameron–Martin space elements ...
Sang Kil Shim, Jae Gil Choi
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Approximate Functionals for Multistate Density Functional Theory [PDF]

open access: yes
Recently Lu and Gao [J. Phys. Chem. Lett. 13, 33, 7762-7769 (2022)] published a new, rigorous density functional theory for excited states and proved that the projection of the kinetic and electron repulsion operators into the subspace of the lowest ...
Alexander, Humeniuk
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Weierstrass Analytic Functions

open access: yesMathematische Annalen, 1966
Weierstrass introduced a complete analytic function as a set consisting of a power series and all its analytic continuations. This definition — a fundamental expansion of Lagrange’s introduction of a function as a power series — was formany decades the only alternative to the classical introduction of functions as laws or rules associating or pairing ...
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Effective analytic functions

open access: yesJournal of Symbolic Computation, 2005
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Reconstruction of linear functionals on classes of analytic functions of two variables on the basis of generalized information [PDF]

open access: yes, 1993
Для класів аналітичних функцій, означених за допомогою 2-вимірної композиції Адамара, за­пропоновано метод відновлення лінійних функціоналів на основі блендінгових конструкцій; вказані найкращі методи відновлення, знайдені точні оцінки похибки.For ...
Вакарчук, С.Б.
core  

Home - About - Disclaimer - Privacy