Results 151 to 160 of about 2,072 (306)
Development of semi-empirical exchange- correlation functionals [PDF]
Kohn-Sham density functional theory (DFT) is the most widely-used method for quantum chemical calculations. For most chemical properties it offers relatively accurate results for a relatively low computational cost.
Keal, Thomas W., Keal, Thomas W
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Large deviations of non-degenerate two-sample von Mises functionals. [PDF]
The asymptotics of large deviation probabilities for two-sample non degenerate von Mises functionals and U- statistics of arbitrary degree is investigated. We find explicitly the main term of this asymptotics.
Evgueni Ponikarov, Yakov Nikitin
core
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Two Discrete Inequalities of Grüss Type Via Pólya-Szegö and Shisha Results for Real Numbers [PDF]
Some new Grüss type discrete inequalities for nonnegative real numbers and applications for the moments of guessing mappings are ...
Dragomir, Sever S, Khan, Lutfar R
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Shape diagrams for 2D compact sets - Part II: analytic simply connected sets. [PDF]
International audienceShape diagrams are representations in the Euclidean plane introduced to study 3-dimensional and 2-dimensional compact convex sets. However, they can also been applied to more general compact sets than compact convex sets.
Rivollier, Séverine +2 more
core
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interpolation by analytic functions [PDF]
openaire +2 more sources

