Results 61 to 70 of about 309,134 (277)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Analytic Coulomb matrix elements in the lowest Landau level in disk geometry
, 2001 Using Darling's theorem on products of generalized hypergeometric series an analytic expression is obtained for the Coulomb matrix elements in the lowest Landau level in the representation of angular momentum.
Cappelli A. +7 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Local Observability of Systems on Time Scales
Abstract and Applied Analysis, 2013 Analytic systems on an arbitrary time-scale are studied. As particular cases they include continuous-time and discrete-time systems. Several local observability properties are considered. They are characterized in a unified way using the language of real
Zbigniew Bartosiewicz
doaj +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Test Instrument Validation of Two Dimensional Geometry Using Rasch Model
MEJ (Mathematics Education Journal), 2020 The purpose of this study is to describe the results of the analysis of the quality of the mathematical students' initial ability in the field of geometry concepts through the Rasch model. This research is descriptive qualitative research at a university
Eyus Sudihartinih, Sufyani Prabawanto
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu +14 more
wiley +1 more source
Geometric Representations of Interacting Maps
International Journal of Mathematics and Mathematical Sciences, 2010 Tropical geometry is a kind of dynamical scale transform which connects automata with real rational dynamics. Real rational dynamics are deeply studied from global analytic viewpoints.
Tsuyoshi Kato
doaj +1 more source