Results 41 to 50 of about 26,137 (301)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The geometry of visual experience [PDF]
, 2007 In this thesis I examine what the geometry of visual experience is. This is a question which to some has had an a priori answer, and to some its relevance to philosophy has been considered questionable.
Meadows, Phillip
core
Derived Hom spaces in rigid analytic geometry
, 2021 International audienceWe construct a derived enhancement of Hom spaces between rigid analytic spaces. It encodes the hidden deformation-theoretic informations of the underlying classical moduli space.
Porta, Mauro, Yu, Tony Yue
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Analytic Kramer kernels, Lagrange-type interpolation series and de Branges spaces
, 2011 The classical Kramer sampling theorem provides a method for obtaining orthogonal sampling formulas. In particular, when the involved kernel is analytic in the sampling parameter it can be stated in an abstract setting of reproducing kernel Hilbert spaces
Hernández-Medina, Miguel A. +7 more
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CTE Workshop Proceedings, 2019 As a result of literature analysis the expediency of free access of bachelors majoring in Computer Sciences and Information Technologies to modern information educational resources, in particular, e-learning courses in the process of studying ...
Oksana M. Hlushak +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
, 2009 Motivated by the well-known lack of archimedean information in algebraic geometry, we define, formalizing Ostrowski's classification of seminorms on Z, a new type of valuation of a ring that combines the notion of Krull valuation with that of a ...
Paugam, Frédéric, Frédéric Paugam
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