Results 41 to 50 of about 26,309 (261)

Automated Devices in Taiwan’s Telemedicine Industry

open access: yesInternational Journal of Automation and Smart Technology, 2013
Telemedicine industry generally refers to the application of media technology to overcome the limits of time and space and to interactive medical professional consulting and advisory services so that doctors may attend remote video conferences and ...
Li-Lun Yeh
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Deriving Priorities the Alternatives in an Analytic Hierarchy Process [PDF]

open access: yesInternational Journal of Research in Industrial Engineering, 2014
The data envelopment analysis (DEA) is a mathematical programming technique, which is used for evaluating relative efficiency of decision making units (DMUs). However, the DEA does not provide more information about the efficient DMUs.
S. Khoshfetrat, F. Hosseinzadeh-Lotfi
doaj   +2 more sources

METHOD OF REGIONAL INNOVATIVE CLIMATE ASSESSMENT

open access: yesДискурс, 2016
The main elements of innovative development provision at the regional level are presented; methods of bringing to compromise interests of innovative activity participants are studied.
M. A. Kosuhina
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

A Clarification of “Remarks on the Analytic Hierarchy Process” [PDF]

open access: yesManagement Science, 1990
The replies by Saaty (1990) and by Harker and Vargas (1990) to my remarks on the Analytic Hierarchy Process (Dyer 1990) are useful in focusing attention on areas of disagreement regarding the AHP, and provide readers with sufficient information to form their own opinions.
openaire   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Accommodating Analytic Hierarchy Process (AHP) for Elective Courses Selection

open access: yesIJIE (Indonesian Journal of Informatics Education), 2019
The determination of elective courses for students is one of many things that require some complex considerations. This complexity is motivated by psychological and non-psychological factors of human beings such as: learning motivation, lecturer and ...
Khresna Bayu Sangka, Binti Muchsini
doaj   +1 more source

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