Results 151 to 160 of about 1,113,738 (296)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Beyond Remodeling: Four Structural-Functional Recovery Patterns as a Framework for Interpreting Ventricular Recovery After Reperfused STEMI. [PDF]

Biomedicines
Crăciun-Mirescu A, Mirea O, Toader DE, Berceanu MC, Rădulescu VM, Moise CG, Delcea RD, Militaru C, Militaru C.   +8 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Mechanics of materials and structures /

, 1994
A wide range of topics in the area of mechanics of materials and structures are covered in this volume, ranging from analysis to design. There is no special emphasis on a specific area of research.
Bieniek Symposium on Mechanics of Materials and Structures(1993 :University of Virginia), Voyiadjis, G. Z., Joint Mechanics Meeting of ASME, ASCE, SES(1st :1993 :Charlottesville, Va.), Bank, Lawrence Colin, Jacobs, Laurence J.   +4 more
core  

Comment on "Early Life Food Desert Status Is Associated With Alpha and Gamma Tocopherol Levels and Infant Lung Function". [PDF]

Pediatr Pulmonol
Mahida K, Jagtap SR.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

The Simplest Complexity: The Story of the Three-Body Problem. [PDF]

Entropy (Basel)
Kol B.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

A gravitational theory of quantum mechanics [PDF]

An explanation for quantum mechanics is given in terms of a classical theory (general relativity) for the first time. Specifically, it is shown that certain structures in classical general relativity can give rise to the non-classical logic normally ...
Hadley, Mark J.
core  

Glock on analytic philosophy and history

Chapter four of Glock’s wide-ranging and incisive book ‘What is Analytic Philosophy?’, which is entitled ‘History and Historiography’, explores the relationship between analytic philosophy and history.
Alvarez, Maria
core   +1 more source