Results 111 to 120 of about 295,652 (218)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

A visual analytic method to investigate patterns and structures of missing data. [PDF]

PLoS One
Ruddle RA.
europepmc   +1 more source

A simple analytic method for estimating T2 in the knee from DESS. [PDF]

Magn Reson Imaging, 2017
Sveinsson B, Chaudhari AS, Gold GE, Hargreaves BA.   +3 more
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Enhanced FPGA-based smart power grid simulation using Heun and Piecewise analytic method. [PDF]

Sci Rep
Gul U, Raza Ur Rehman HM, Gul MJ, Mezquita GM, Barrera AEP, Ashraf I.   +5 more
europepmc   +1 more source

Analytic method for evaluating players' decisions in team sports: Applications to the soccer goalkeeper. [PDF]

PLoS One, 2018
Lamas L, Drezner R, Otranto G, Barrera J.   +3 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

A decision-analytic method to evaluate the cost-effectiveness of remote monitoring technology for chronic depression. [PDF]

Int J Technol Assess Health Care
Sun X, Wissow L, Liu S.
europepmc   +1 more source

Combining distributed regression and propensity scores: a doubly privacy-protecting analytic method for multicenter research. [PDF]

Clin Epidemiol, 2018
Toh S, Wellman R, Coley RY, Horgan C, Sturtevant J, Moyneur E, Janning C, Pardee R, Coleman KJ, Arterburn D, McTigue K, Anau J, Cook AJ.   +12 more
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source