Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The Use of the AHP in Civil Engineering Projects [PDF]
Most engineering, economic, social and institutional decisions are made with explicit notions of optimal behavior and implicit human motivations. In such a process, manipulation of both tangible and intangible data and satisfaction of multiple criteria ...
György Kadocsa, András Farkas
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Establishing Indicators and an Analytic Method for Moisture Susceptibility and Rutting Resistance Evaluation Using a Hamburg Wheel Tracking Test. [PDF]
Materials (Basel), 2020 Wang WH, Huang CW.
europepmc +1 more source
Does AHP help us make a choice? - An experimental evaluation
, 2011 Author's pre-print version dated 2. August 2010 deposited in Munich Personal RePEc Archive. Final version published by Palgrave Macmillan; available online at http:// www.palgrave-journals.com/In this paper, we use experimental economics methods to test ...
Kaplan, T. +7 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
A semi-analytic spectral method for elliptic partial differential equations
Electronic Journal of Differential Equations, 2017 In this article we present a semi-analytic method for solving elliptic partial differential equations. The technique is based on using a spectral method approximation for the second-order derivative in one of the spatial directions followed by ...
Ishtiaq Ali, Maliha Tahseen Saleem
doaj
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Meta-analytic method reveal a significant association of theBDNF Val66Met variant with smoking persistence based on a large samples. [PDF]
Pharmacogenomics J, 2020 Zhao H, Xiong S, Li Z, Wu X, Li L.
europepmc +1 more source