Results 151 to 160 of about 14,778,251 (296)

Decision Making with the Analytic Network Process

, 2017
One of the most advanced and complex multi- criteria decision-making methods is the analytic network process (ANP). This method supports modelling dependencies and feedback between elements in the network. For this reason, the ANP is one of the most appropriate methods for making decisions in fields that are characterised by existing dependencies of ...
Divjak, Blaženka, Kadoić, Nikola, Begičević Ređep, Nina   +2 more
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Dynamic Analytic Network Process [PDF]

Hradec Economic Days, 2018
openaire   +1 more source

Theory of the analytic hierarchy and analytic network processes – examples. Part 2.2

Sistemnì Doslìdženâ ta Informacìjnì Tehnologìï, 2013
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openaire   +3 more sources

Construction of an Interpretive Structural Model-Analytic Network Process model for preschool children's drowning risk factors based on the Haddon matrix. [PDF]

Front Public Health
Ma F, Luo D, Liu H, Zhao G.
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Surgical Intensity and Specialization Preferences in Healthcare: An Operation- and Process-Management Perspective Using Bibliometric Analysis, Cognitive Mapping and Analytic Network Process (ANP). [PDF]

Healthcare (Basel)
Kılıç Y, Duzdar I, Hamlaoui O, Tozan H, El Fqih MA.   +4 more
europepmc   +1 more source

An Evaluation of Environmental Governance in Urban China Based on a Hesitant Fuzzy Linguistic Analytic Network Process. [PDF]

Int J Environ Res Public Health, 2018
Gao X, Shi C, Zhai K.
europepmc   +1 more source