Sex Differences in the Prevalence and Correlates of Sleep Disturbance Among Indonesian Stroke Survivors: A Population-Based Study of 7,147 Individuals. [PDF]
Susanty S +7 more
europepmc +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Admission Laboratory-Based Prediction of Six-Month Mortality After COVID-19 Hospitalization: Model Development, Bootstrap Internal Validation, and Single-Center Temporal Validation. [PDF]
Çelik O, Gülcü O.
europepmc +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Symptom-Domain Correlates of Self-Reported Anxious Distress in Outpatients With Major Depressive Disorder. [PDF]
Oga S +7 more
europepmc +1 more source
Modern sample preparation methods for POPs
Interview.Persistent organic pollutants (POPs) pose an on-going threat to human health, but are often trapped within environmental samples, thereby making analysis challenging.
Ramos, Lourdes
core
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Perioperative shingles diagnosis does not influence prosthetic joint infection rates after shoulder arthroplasty. [PDF]
Nakken ER +3 more
europepmc +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Moments of Change in Group Psychotherapy: Exploring Therapeutic Factors and Relational Processes. [PDF]
Chelios K, Vlachos II.
europepmc +1 more source

