Results 211 to 220 of about 340,608 (289)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Digital behavior and anxiety in the post-pandemic era: a five-year analysis of screen time, sleep, and behavioral risk profiles. [PDF]

Front Public Health
Liu W.
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Childhood attention deficit hyperactivity disorder traits, societal exclusion and midlife psychological distress. [PDF]

Nat Ment Health
John A, O'Nions E, Corrigan L, Cotton J, Donnellan WJ, Nimmons D, Shelford H, Eshetu A, Saunders R, El Baou C, Stewart GR, Cheung RW, Desai R, McKechnie DG, Suh JW, Mandy W, Gaysina D, Pavlopoulou G, Asherson P, Agnew-Blais J, Stott J.   +20 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

OH-MEMA: An Integrated One Health Mixed-Effects Modeling Approach for Syndromic Surveillance. [PDF]

J Clin Med
Basheer A, Khiabani PM, Jentner W, Wendelboe A, Vogel JR, Kuhn KG, Wimberly MC, Hougen D, Ebert D.   +8 more
europepmc   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Assessment of clinical and neuroimaging efficacy of treatment targeting tau pathology in mild cognitive impairment and mild to moderate Alzheimer's disease with hydromethylthionine mesylate using external control data. [PDF]

J Prev Alzheimers Dis
Schelter BO, Shiells H, Lo S, Nazlee N, Evans E, Bentham P, Gauthier S, Zetterberg H, Wilcock GK, Froelich L, Burns A, MacSweeney E, Ballard C, Yu JT, Choon TS, Asvatourian V, Muehlemann N, Priel J, Kook K, Sullivan T, Downie D, Miller S, Pringle C, Storey JMD, Baddeley T, Harrington CR, Staff R, Sandu AL, Hull C, Stefanacci R, Wischik CM, Alzheimer's Disease Neuroimaging Initiative.   +31 more
europepmc   +1 more source