Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Redefining autism in adulthood interventions <i>in</i> and <i>through</i> social virtual environments: an exploratory cross-cultural study. [PDF]
Grillo VD, Tanini G, Rana FC, Venuti P.
europepmc +1 more source
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Family Vaccination Context Predicts HPV Vaccine Uptake Among Medical Students. [PDF]
Harb F +5 more
europepmc +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Respiratory-Support Phenotypes and In-Hospital Mortality in Pediatric Postprocedural Respiratory Complications. [PDF]
Samawi M, Samawi H, Shah GH, Al-Saleh M.
europepmc +1 more source
Repeated sampling of different individuals within the same clusters to improve precision of longitudinal estimators: the DISC design. [PDF]
Downey J, Kenny A.
europepmc +1 more source
Reappraisal of Mental Illness-Related Beliefs During Psychiatric Clinical Exposure: Perceived Dangerousness, Ruminative Thought Style, and Cognitive-Metacognitive Characteristics. [PDF]
Güneysu İ +6 more
europepmc +1 more source
An interpretable Hallmark pathway activity classifier for distinguishing CIN3/HSIL from invasive cervical squamous carcinoma: Development, external validation, and feature stability assessment. [PDF]
Jia M +8 more
europepmc +1 more source
Health Care Transition Experiences for Rural and Urban Autistic Adolescents and Young Adults: A Qualitative Analysis. [PDF]
Zhang E +6 more
europepmc +1 more source

