Results 101 to 110 of about 50,256 (293)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Designing a model for selection of air pollution control equipment using fuzzy logic

بهداشت و ایمنی کار, 2014
Introduction: Air health is an important environmental issue which has been endangered in recent years due to application of advanced technologies used for improving the financial welfare and relative prosperity of humans. Making use of pollution control
F. Golbabaei, A. Azar, M. Ganji Kazemian   +2 more
doaj  

exoALMA. VIII. Probabilistic Moment Maps and Data Products Using Nonparametric Linear Models

The Astrophysical Journal Letters
Extracting robust inferences on physical quantities from disk kinematics measured from Doppler-shifted molecular line emission is challenging due to the data’s size and complexity.
Thomas Hilder, Andrew R. Casey, Daniel J. Price, Christophe Pinte, Andrés F. Izquierdo, Caitlyn Hardiman, Jaehan Bae, Marcelo Barraza-Alfaro, Myriam Benisty, Gianni Cataldi, Pietro Curone, Ian Czekala, Stefano Facchini, Daniele Fasano, Mario Flock, Misato Fukagawa, Maria Galloway-Sprietsma, Himanshi Garg, Cassandra Hall, Iain Hammond, Jane Huang, John D. Ilee, Kazuhiro Kanagawa, Geoffroy Lesur, Cristiano Longarini, Ryan Loomis, Ryuta Orihara, Giovanni Rosotti, Jochen Stadler, Richard Teague, Hsi-Wei Yen, Gaylor Wafflard, Andrew J. Winter, Lisa Wölfer, Tomohiro C. Yoshida, Brianna Zawadzki   +35 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Analytic Philosophy in America

, 2014
This collection of recent and unpublished essays traces milestones in the field of analytic philosophy from its beginnings in Britain and Germany in the late nineteenth and early twentieth centuries, through its subsequent growth in the United States, up
Scott Soames
core   +1 more source

Ensemble modeling of coronal mass ejection dynamics and forecasts at 1 AU with a semi-analytic flux-rope model

Astronomy & Astrophysics
Aims. This study quantifies how uncertainty in physically meaningful coronal mass ejection (CME) and solar-wind inputs propagates into forecast-relevant diagnostics from eruption through heliospheric evolution.
Stamkos S., Patsourakos S., Vourlidas A., Paouris E.   +3 more
doaj   +1 more source

Analytic spread of binomial edge ideals

14 pages, comments are ...
Camps-Moreno, Eduardo, Dey, Deblina, Dey, Souvik, Ha, Tai Huy, Landsittel, Stephen, Oltsik, Benjamin, Zamir, Shahriyar Roshan, Van Tuyl, Adam   +7 more
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An investigation into the statistical properties of TB episodes in a South African community with high HIV prevalence.

, 2011
Continuous differential equations are often applied to small populations with little time spent on understanding uncertainty brought about by small-population effects.
Dodd, Peter, Dodd P., Peter Dodd, Pretorius, Carel, Robin Wood, Pretorius C., Wood R., Wood, Robin, Carel Pretorius   +8 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source