Results 131 to 140 of about 3,236,909 (304)

Immunosensors in biology and medicine: Analytical capabilities, problems, and prospects

, 2020
The current status of research in immunosensors was considered. Primary attention was focused on electrochemical, piezoelectric, and optical immunosensors. The analytical capabilities of these devices were discussed.
Khaldeeva E., Medyantseva E., Budnikov G.   +2 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Long-Term Performance and Bulk-Isotope Effects in Methane Clumped-Isotope Measurements Using a 253 Ultra HR-IRMS. [PDF]

Rapid Commun Mass Spectrom
Zhang N, Gilbert A, Nakagawa M, Surma J, Meissner JGC, Mohn J, Bernasconi SM, Ueno Y, Yoshida N.   +8 more
europepmc   +1 more source

The Analyst : The Journal of the Society for Analytical Chemistry

, 1959
620 hal,;ill,;27 ...
Society for Analytical Chemistry
core  

Analytical sensing with green nanomaterials

The rapid and sensitive recognition response of sensor platforms is of paramount importance. Nanomaterials have emerged as a key area of research on the design and fabrication of more sensitive and environmentally-friendly sensor platforms. Nanomaterials-
Keçili, Rüstem, Hussain, Chaudhery Mustansar, Ghorbani-Bidkorpeh, Fatemeh, Hussain, Chaudhery Ghazanfar, Rüstem Keçili, Chaudhery Ghazanfar Hussain, Chaudhery Mustansar Hussain, Fatemeh Ghorbani-Bidkorpeh   +7 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

TIMS Techniques for Measuring Strontium Isotope Ratios in Apatite Grains and Application to Igneous Rock Petrology. [PDF]

Rapid Commun Mass Spectrom
Neto C, de Morisson Valeriano C, Paravidini G, Bruno H, Carvalho M, Almeida R, Peixoto C, Bersan S, Carvalho M, Heilbron M.   +9 more
europepmc   +1 more source

The Analyst : The Journal of the Society for Analytical Chemistry

, 1972
1008 hal,;ill,;27 ...
Society for Analytical Chemistry
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source