Results 141 to 150 of about 328,185 (261)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Retracted: Application of Cement-Based Composite Nanomaterials in Prefabricated Thin-Wall Light Steel Structure Composite Wall

International Journal of Analytical Chemistry, 2023
International Journal of Analytical Chemistry
doaj   +1 more source

Analytical chemistry in front of the curtain! [PDF]

Anal Bioanal Chem
Rosenberg E, Krska R.
europepmc   +1 more source

Teaching with simulation tools to introduce the basics of analytical chemistry instrumentation. [PDF]

Anal Bioanal Chem, 2022
Largy E, Alies B, Condesse G, Gaubert A, Livingston T, Gaudin K.   +5 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Estrogens and Progestogens in Environmental Waters: Analytical Chemistry and Biosensing Perspectives on Methods, Challenges, and Trends. [PDF]

Anal Chem
Lalik A, Szreder J, Grymel M, Żabczyński S, Bajkacz S, Pielok M, Cieślik M, Kicińska A, Wawrzkiewicz-Jałowiecka A.   +8 more
europepmc   +1 more source

Trends and challenges in analytical chemistry for multi-analysis of illicit drugs employing wastewater-based epidemiology. [PDF]

Anal Bioanal Chem, 2023
de Oliveira AFB, de Melo Vieira A, Santos JM.   +2 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Ionic Liquids in Analytical Chemistry: Fundamentals, Technological Advances, and Future Outlook. [PDF]

Anal Chem
Zeger VR, Thapa B, Shamsaei D, DeLair JF, Taylor TL, Anderson JL.   +5 more
europepmc   +1 more source

Recent trends in (bio)analytical chemistry. [PDF]

Anal Bioanal Chem, 2021
Gauglitz G, Baeumner AJ.
europepmc   +1 more source