Results 301 to 310 of about 4,290,360 (367)

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

open access: yesMolecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef   +10 more
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Nanozyme-Enabled Analytical Chemistry.

Analytical Chemistry, 2021
■ CONTENTS Nanozymes with Higher Activity 312 Improving the Inherent Activity of Nanozymes 313 Acquired Activity of Nanozymes 313 Nanozymes with Better Specificity 314 Improving the Inherent Specificity of Nanozymes 314 Acquired Specificity of Nanozymes ...
Sirong Li   +4 more
semanticscholar   +1 more source

Ionic Liquids in Analytical Chemistry: Applications and Recent Trends

Current Analytical Chemistry, 2021
Ionic liquids (ILs) are a unique class of compounds consisting exclusively of cations and anions that possess distinctive properties such as low volatility, high thermal stability, miscibility with water and organic solvents, electrolytic conductivity
G. M. Merone   +7 more
semanticscholar   +1 more source

Emerging Extraction Strategies in Analytical Chemistry.

Analytical Chemistry, 2020
Extraction in the context of analytical chemistry (analytical-scale extraction) is defined as "the transfer of target analyte from one phase to a different phase where further processing and analysis occurs".1 The target analyte is thus isolated from the
F. Hansen, S. Pedersen‐Bjergaard
semanticscholar   +1 more source

Wearable Chemical Sensors: Emerging Systems for On-body Analytical Chemistry.

Analytical Chemistry, 2020
With the emergence of mobile devices and digital medicine, wearable sensors have received tremendous recent attention across many applications related to monitoring the wearer's conditions and surroundings.
J. Sempionatto   +3 more
semanticscholar   +1 more source

Process Analytical Chemistry [PDF]

open access: possibleAnalytical Chemistry, 2003
This review of process analytical chemistry is an update to the previous review on this subject published in 1995(A2). The time period covered for this review includes publications written or published from late 1994 until early 1999, with the addition of a few classic references pointing to background information critical to an understanding of a ...
Mel V. Koch   +2 more
openaire   +3 more sources

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