Results 41 to 50 of about 1,077,197 (285)

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

Determining how atmospheric carbon dioxide concentrations have changed during the history of the Earth [PDF]

, 2011
The reconstruction of ancient atmospheric carbon dioxide concentrations is essential to understanding the history of the Earth and life. It is also an important guide to identifying the sensitivity of the Earth system to this greenhouse gas and ...
Badger, Marcus P. S., Harrison, Timothy G., Pancost, Richard D.   +2 more
core   +1 more source

Radial Distribution of Production Rates, Loss Rates and Densities Corresponding to Ion Masses <=40 amu in the Inner Coma of Comet Halley: Composition and Chemistry

, 2005
In this paper we have studied the chemistry of C, H, N, O, and S compounds corresponding to ions of masses
Allen, Altwegg, Altwegg, Altwegg, Anicich, Anicich, Anicich, Anil Bhardwaj, Balsiger, Balsiger, Bhardwaj, Bhardwaj, Bhardwaj, Bhardwaj, Bhardwaj, Bhardwaj, Bhardwaj, Bhardwaj, Boice, Crovisier, Eberhardt, Eberhardt, Eberhardt, Eberhardt, Festou, Festou, Geiss, Gringauz, Haberli, Haberli, Haider, Haider, Huebner, Huebner, Huebner, Ip, Khare, Korth, Krankowsky, Marconi, Marconi, Marconi, Marconi, Meier, Meier, Mendis, Michael, Millar, Mitchell, Mitchell, Mitchell, Murad, Rao, Reme, S.A. Haider, Schmidt, Slanina, Wegmann, Wegmann   +58 more
core   +1 more source

Food Chemistry: Food quality and new analytical approaches [PDF]

, 2016
Peer ...
Coelho, L., Coelho, M. M., Guardia, Miguel de la, Ruiz-Capillas, C., Tarley, C. R.   +4 more
core   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Analytical and applied chemistry: A compilation [PDF]

Analytical chemistry and chemical processes and applied chemistry are presented.

core   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Atomic and molecular complex resonances from real eigenvalues using standard (hermitian) electronic structure calculations

, 2015
Complex eigenvalues, resonances, play an important role in large variety of fields in physics and chemistry. For example, in cold molecular collision experiments and electron scattering experiments, autoionizing and pre-dissociative metastable resonances
Haritan, Idan, Kaprálová-Žďánská, Petra Ruth, Landau, Arie, Moiseyev, Nimrod   +3 more
core   +2 more sources

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Analytical Chemistry [PDF]

Exam paper for the first semester (Department of Applied Physics and Engineering Mathematics, National Diploma: Analytical ...
University of Johannesburg
core   +3 more sources