The enzymatic determination of glucose in carbonated beverages: a useful tool for the undergraduate students to learn the basis of enzymatic analysis and the comparison of two analytical methods [PDF]
The importance of enzymatic analysis in biochemistry, clinical chemistry and food chemistry is undoubted. The course "Applied Biochemistry" in our Faculty is aimed to undergraduate students of Chemistry and Biochemistry.
Blanco-Lopez, Angel+4 more
core
MALDI-MS at the Ingenieurschule Burgdorf: The Technique, Some Applications and Expected Benefits for the Education in Modern Analytical Chemistry [PDF]
Analytical chemistry is changing rapidly, new methods are developed and introduced in the analytical laboratories. Parallel to this progress, the chemical industry is undergoing pronounced changes: it is focusing more and more on the life sciences ...
Schär, Martin
core +2 more sources
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti+2 more
wiley +1 more source
Transformers and Large Language Models for Chemistry and Drug Discovery [PDF]
Language modeling has seen impressive progress over the last years, mainly prompted by the invention of the Transformer architecture, sparking a revolution in many fields of machine learning, with breakthroughs in chemistry and biology. In this chapter, we explore how analogies between chemical and natural language have inspired the use of Transformers
arxiv
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr+4 more
wiley +1 more source
This Annual Report covers from 1 January to 31 December ...
core
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang+9 more
wiley +1 more source
Conventional Quantum Chemical Correlation Energy versus Density-Functional Correlation Energy [PDF]
We analyze the difference between the correlation energy as defined within the conventional quantum chemistry framework and its namesake in density-functional theory. Both quantities are rigorously defined concepts; one finds that $E_c^{QC} \geq E_c^{DFT}$.
arxiv
Analytical chemistry of lanthanides [PDF]
The work described in this thesis consists of nine chapters.The first chapter is a general introduction, where lanthanide elements and their application are presented. Candoluminescence is defined as a type of solid state luminescence excited by hydrogen-
Al-Sowdani, Kamail Hussain
core +1 more source
Analytical measurement: measurement uncertainty and statistics [PDF]
TrainMiC® is a European programme for lifelong learning on how to interpret the metrological requirements in chemistry. It is operational across many parts of Europe via national teams. These teams use shareware pedagogic tools which have been harmonised
BETTENCOURT DA SILVA Ricardo+12 more
core +1 more source